Cyril Planchais, Alejandra Reyes-Ruiz, Robin Lacombe, Alessandra Zarantonello, Maxime Lecerf, Margot Revel,Lubka T. Roumenina, Boris P. Atanasov, Hugo Mouquet, Jordan D. Dimitrov.
Evolutionary trajectory of the physicochemical mechanism of interaction of SARS-CoV-2 spike protein with ACE2.
Protein Science 2022 Nov;31(11):e4447.
doi: 10.1002/pro.4447
Ruiz Reyes A, S Delignant, V Daventure, A Mimoun, D J Dimitrov, S Lacroix-Desmazes.
Induction of neonatal tolerance to therapeutic FVIII in hemophilia A.
Hamostaseologie 2023; 43(S 01): S37-S38.
doi: 10.1055/s-0042-1760514 (Publication in conference proceeding/workshop)
Angelina Mimoun, Melissa Bou-Jaoudeh, Sandrine Delignat, Victoria Daventure, Alejandra Reyes Ruiz, Maxime Lecerf, Aurélien Azam, Remi Noe, Ivan Peyron, Olivier D. Christophe, Peter J. Lenting, Valérie Proulle, Jenny McIntosh, Amit C. Nathwani, Jordan D. Dimitrov , Cécile V. Denis, Sébastien Lacroix-Desmazes.
Transplacental delivery of therapeutic proteins by engineered IgG: a step towards perinatal replacement therapy.
Journal of Thrombosis and Haemostasis. Volume 21, Issue 9, September 2023, 2405-2417.
doi: 10.1016/j.jtha.2023.05.021
Reyes Ruiz A, Bhale AS, Venkataraman K, Dimitrov JD, Lacroix-Desmazes S.
Binding Promiscuity of Therapeutic Factor VIII.
Thromb Haemost. 2024 Jul 16.
doi: 10.1055/a-2358-0853.
Reyes-Ruiz A, Sandrine Delignat, Aishwarya Sudam Bhale, Victoria Daventure, Robin V. Lacombe, Leslie Dourthe, Olivier Christophe, Sune Justesen, Krishnan Venkataraman, Jordan D. Dimitrov, Sebastien Lacroix-Desmazes.
Binding of therapeutic Fc-fused factor VIII to FcRn at neutral pH associates with poor half-life extension.
Under revision at Haematologica.
Hassan S, Baselli G, Mollica L, Rossi RL, Chand H, El-Beshlawy A, Elalfy M, Ramanan V, Eshghi P, Karimi M, Palla R, Rosendaal FR, Peyvandi F.
Predicting inhibitor development using a random peptide phage-display library approach in the SIPPET cohort.
Blood Adv. 2024 Jun 11;8(11):2880-2889.. PMID: 38593222; PMCID: PMC11176960.
doi: 10.1182/bloodadvances.2023011388
Chand H, Hassan S, Cairo A, Palla R, Peyvandi F.
Effect of DNA methylation on inhibitor development in Hemophilia A patients treated with FVIII concentrates.
Under Revision in Research and Practice in Thrombosis and Haemostasis
Porcheddu, V., G. Lhomme, R. Giraudet, E. Correia, and B. Maillere.
2024. The self-reactive FVIII T cell repertoire in healthy individuals relies on a short set of epitopes and public clonotypes.
Frontiers in immunology 15: 1345195.
Oomen I, Verhagen M, Miranda M, Allacher P, Beckers EAM, Blijlevens NMA, van der Bom JG, Coppens M, Driessens M, Eikenboom JCJ, Fijnvandraat K, Hassan S, van Heerde WL, Hooimeijer HL, Jansen JH, Kaijen P, Leebeek FWG, Meijer D, Paul H, Rijpma SR, Rosendaal FR, Smit C, van Vulpen LFD, Voorberg J, Schols SEM, Gouw SC.
The spectrum of neutralizing and non-neutralizing anti-FVIII antibodies in a nationwide cohort of 788 persons with hemophilia A.
Front Immunol. 2024 Feb 22;15:1355813. PMID: 38455035; PMCID: PMC10918462.
doi: 10.3389/fimmu.2024.1355813
Dargaud Y, Leuci A,
Efanesoctocog alfa: the renaissance of Factor VIII replacement therapy.
Haematologica. 2024 Aug 1;109(8):2436-2444.
doi: 10.3324/haematol.2023.284498
Toshkova N, Zhelyzkova V, Reyes-Ruiz A, Haerens E, de Castro Deus M, Lacombe RV, Lecerf M, Gonzalez G, Jouvenet N, Planchais C, Dimitrov JD.
Temperature sensitivity of bat antibodies links metabolic state of bats with antigen-recognition diversity.
Nat Commun. 2024 Jul 13;15(1):5878.
doi: 10.1038/s41467-024-50316-x
Alejandra Reyes-Ruiz, Jordan D. Dimitrov.
How can polyreactive antibodies conquer rapidly evolving viruses?
Trends in Immunology, Elsevier, 2021, 42 (8), pp.654-657.
https://doi.org/10.1016/j.it.2021.06.008
Alejandra Reyes-Ruiz, Jordan D. Dimitrov.
Microbial symphony orchestrated by mucosal IgA.
Cell Mol Immunol., 2022 Apr;19(4):456-457.
https://doi.org/10.1038/s41423-021-00819-0